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Freezing of Dimethyl Sulfoxide

Information

Question I just received a bottle of Dimethyl Sulfoxide. Much of the contents have solidified to a hard-gelatinous state, though there's some liquid remaining. Is this unusual? Should I be concerned about the purity/efficacy of the remaining liquid? Is there a way to get back to 100% liquid state?
Answer

It is common for Dimethyl Sulfoxide (DMSO)to solidify during shipment and storage in cooler climates. According to most references, this chemical has a freezing point of approximately 18.5 degrees Celsius, although there are indications that it supercools easily. If you are in a cooler geographic location, it seems likely that this product would be exposed to temperatures below the freezing point of this material.
The product should be able to be restored to a liquid form with gentle and careful heating above the freezing point; gentle agitation should also help speed the process. Although DMSO is heat-stable, we do not recommend heating the product beyond 40o C because of safety concerns. To avoid pressure build-up within the container, the bottle cap or container opening should be loosened to allow venting. Please review the MSDS prior to handling the chemical.

Once the entire contents are returned to the liquid state, and assuming any remaining liquid from the frozen state was not compromised, there is no information to indicate that this material would not meet the original label specifications.

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File PDFCIQA-0112 Rev. 1.pdf
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